Glycyl Radical Enzymes Catalyzing the Dehydration of Two Isomers of N-Methyl-4-hydroxyproline

Author:

Jiang Li12345,Yang Yiqian6,Huang Lin2,Zhou Yan2,An Junwei2,Zheng Yuchun1,Chen Yiwei1ORCID,Liu Yanhong7,Huang Jianhui2ORCID,Ang Ee Lui8ORCID,Zhao Suwen910ORCID,Zhao Huimin11ORCID,Liao Rongzhen6ORCID,Wei Yifeng8,Zhang Yan12345ORCID

Affiliation:

1. New Cornerstone Science Laboratory, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China

2. Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China

3. Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin University, Tianjin 300072, China

4. Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China

5. Department of Chemistry, Tianjin University, Tianjin 300072, China

6. Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica, Hubei Key Laboratory of Materials Chemistry and Service Failure, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China

7. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China

8. Singapore Institute of Food and Biotechnology Innovation, Agency for Science, Technology and Research (A*STAR), Singapore 138669, Singapore

9. iHuman Institute, ShanghaiTech University, Shanghai 201210, China

10. School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China

11. Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana─Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States

Funder

Agency for Science, Technology and Research

National Key Research and Development Program of China

National Science Fund for Distinguished Young Scholars

New Cornerstone Science Foundation

Advanced Manufacturing and Engineering Programmatic Grant

Publisher

American Chemical Society (ACS)

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