Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme b-Reference-Cited by-同舟云学术

Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme b

Published:2019-06-18 Issue:8 Volume:9 Page:6766-6782
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Milazzo Lisa¹,Gabler Thomas²,Pühringer Dominic³,Jandova Zuzana⁴,Maresch Daniel²,Michlits Hanna²,Pfanzagl Vera²,Djinović-Carugo Kristina³⁵,Oostenbrink Chris⁴^ORCID,Furtmüller Paul G.²^ORCID,Obinger Christian²^ORCID,Smulevich Giulietta¹^ORCID,Hofbauer Stefan²^ORCID

Affiliation:

1. Dipartimento di Chimica “Ugo Schiff”, Università di Firenze, Via della Lastruccia 3-13, I-50019 Sesto Fiorentino (FI), Italy

2. Department of Chemistry, Division of Biochemistry, BOKU−University of Natural Resources and Life Sciences, Muthgasse 18, A-1190 Vienna, Austria

3. Department for Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, A-1030 Vienna, Austria

4. Department of Material Sciences and Process Engineering, Institute of Molecular Modeling and Simulation, BOKU−University of Natural Resources and Life Sciences, A-1190 Vienna, Austria

5. Department of Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, 1000 Ljubljana, Slovenia

Funder

Austrian Science Fund

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acscatal.9b00963

Reference37 articles.

1. Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product

2. Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin