A Bulky and Electron-Rich N-Heterocyclic Carbene–Palladium Complex (SIPr)Ph2Pd(cin)Cl: Highly Efficient and Versatile for the Buchwald–Hartwig Amination of (Hetero)aryl Chlorides with (Hetero)aryl Amines at Room Temperature-Reference-Cited by-同舟云学术

A Bulky and Electron-Rich N-Heterocyclic Carbene–Palladium Complex (SIPr)Ph2Pd(cin)Cl: Highly Efficient and Versatile for the Buchwald–Hartwig Amination of (Hetero)aryl Chlorides with (Hetero)aryl Amines at Room Temperature

Published:2021-07-12 Issue:15 Volume:11 Page:9252-9261
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Ouyang Jia-Sheng¹^ORCID,Liu Siqi²,Pan Bendu¹,Zhang Yaqi¹,Liang Hao¹,Chen Bin¹,He Xiaobo¹,Chan Wesley Ting Kwok³,Chan Albert S. C.¹^ORCID,Sun Tian-Yu⁴,Wu Yun-Dong²⁴⁵^ORCID,Qiu Liqin¹

Affiliation:

1. School of Chemistry, Guangdong Key Lab of Chiral Molecules and Drug Discovery, Sun Yat-sen University, Number 135 Xingangxi Road, Guangzhou 510275, China

2. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

3. Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China

4. Shenzhen Bay Laboratory, Shenzhen, 518132, China

5. Lab of Computational Chemistry and Drug Design, State Key Laboratory of Chemical Oncogenomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China

Funder

Key-Area Research and Development Program of Guangdong Province

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c01929

Reference103 articles.

1. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

2. Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions

3. Synthesis of Imatinib by C–N Coupling Reaction of Primary Amide and Bromo-Substituted Pyrimidine Amine