Controlled Trafficking of Multiple and Diverse Cations Prompts Nucleic Acid Hydrolysis-Reference-Cited by-同舟云学术

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Controlled Trafficking of Multiple and Diverse Cations Prompts Nucleic Acid Hydrolysis

Published:2021-07-02 Issue:14 Volume:11 Page:8786-8797
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Manigrasso Jacopo¹²^ORCID,De Vivo Marco¹^ORCID,Palermo Giulia²³^ORCID

Affiliation:

1. Laboratory of Molecular Modelling & Drug Discovery, Istituto Italiano di Tecnologia, Genoa 16163, Italy

2. Department of Bioengineering, University of California Riverside, Riverside, California 52512, United States

3. Department of Chemistry, University of California Riverside, Riverside, California 52512, United States

Funder

Division of Chemistry

Associazione Italiana per la Ricerca sul Cancro

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c01825

Reference73 articles.

1. Capture of a third Mg 2+ is essential for catalyzing DNA synthesis

2. Watching DNA polymerase η make a phosphodiester bond

3. Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5′ exonuclease activities

4. Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions

5. Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

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