Snapshots of the Catalytic Cycle of the Industrial Enzyme α-Amino-ε-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography
Author:
Affiliation:
1. York Structural Biology Laboratory, Department of Chemistry, University of York, YO10 5DD York, United Kingdom
2. GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom
Funder
GlaxoSmithKline
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.6b03056
Reference18 articles.
1. Industrial production of amino acids by coryneform bacteria
2. Industrial biotransformations for the production of d-amino acids
3. Enzymatic dynamic kinetic resolution of racemic N-formyl- and N-carbamoyl-amino acids using immobilized l-N-carbamoylase and N-succinyl-amino acid racemase
4. Dynamic kinetic resolution: synthesis of optically active α-amino acid derivatives
5. An Improved Racemase/Acylase Biotransformation for the Preparation of Enantiomerically Pure Amino Acids
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1. Through the Looking Glass: Chiral Recognition of Substrates and Products at the Active Sites of Racemases and Epimerases;Chemistry – A European Journal;2020-07-21
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