In Silico Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase-Reference-Cited by-同舟云学术

In Silico Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase

Published:2021-10-28 Issue:21 Volume:11 Page:13733-13743
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Maria-Solano Miguel A.¹²^ORCID,Kinateder Thomas³,Iglesias-Fernández Javier¹⁴^ORCID,Sterner Reinhard³,Osuna Sílvia¹⁵^ORCID

Affiliation:

1. CompBioLab Group, Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona, Maria Aurèlia Capmany 69, Girona 17003, Spain

2. Global AI Drug Discovery Center, College of Pharmacy and Graduate School of Pharmaceutical Science, Ewha Womans University, Seoul 03760, Republic of Korea

3. Institute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, Universitätsstrasse 31, Regensburg 93053, Germany

4. Nostrum Biodiscovery, Carrer de Baldiri Reixac, 10-12, Barcelona 08028, Spain

5. ICREA, Pg. Lluís Companys 23, Barcelona 08010, Spain

Funder

Ministerio de Econom??a y Competitividad

National Research Foundation of Korea

H2020 Marie Sk??odowska-Curie Actions

Human Frontier Science Program

H2020 European Research Council

Ministry for Science and Innovation of Spain

Publisher

American Chemical Society (ACS)

Subject