Ancestral Sequence Reconstruction Enhances Gene Mining Efforts for Industrial Ene Reductases by Expanding Enzyme Panels with Thermostable Catalysts
Author:
Affiliation:
1. Pfizer Global Research and Development, Chemical Research Development, MS 4073 Eastern Point Road, Groton, Connecticut 06340, United States
Funder
Pfizer
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.2c03859
Reference54 articles.
1. Exploring the past and the future of protein evolution with ancestral sequence reconstruction: the ‘retro’ approach to protein engineering
2. Ancestral Reconstruction
3. Ancestral protein reconstruction: techniques and applications
4. Ancestral Sequence Reconstruction: From Chemical Paleogenetics to Maximum Likelihood Algorithms and Beyond
5. Resurrecting ancient genes: experimental analysis of extinct molecules
Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Characterization, structural, and evolutionary analysis of an extremophilic GH5 endoglucanase from Bacillus sp. G131: Insights from ancestral sequence reconstruction;International Journal of Biological Macromolecules;2024-10
2. Rational design of short-chain dehydrogenase DHDR for efficient synthesis of (S)-equol;Enzyme and Microbial Technology;2024-10
3. Application of protein engineering to ene-reductase for the synthesis of chiral compounds through asymmetric reaction;Critical Reviews in Biotechnology;2024-08-12
4. Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape;2024-04-27
5. Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction**;Angewandte Chemie International Edition;2024-03-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3