Structure of the Reductase Domain of a Fungal Carboxylic Acid Reductase and Its Substrate Scope in Thioester and Aldehyde Reduction

Author:

Daniel Bastian123,Hashem Chiam14,Leithold Marlene12,Sagmeister Theo2,Tripp Adrian5ORCID,Stolterfoht-Stock Holly1,Messenlehner Julia5,Keegan Ronan6,Winkler Christoph K.7ORCID,Ling Jonathan Guyang8,Younes Sabry H.H.910,Oberdorfer Gustav5,Abu Bakar Farah Diba8,Gruber Karl12113ORCID,Pavkov-Keller Tea12113ORCID,Winkler Margit14ORCID

Affiliation:

1. acib - Austrian Center of Industrial Biotechnology, Krenngasse 37, 8010Graz, Austria

2. Institute of Molecular Biosciences, University of Graz, Humboldtstraße 50, 8010Graz, Austria

3. BioTechMed-Graz, 8010Graz, Austria

4. Institute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14, 8010Graz, Austria

5. Institute for Biochemistry, Graz University of Technology, Petersgasse 12, 8010Graz, Austria

6. Rutherford Appleton Laboratory, Research Complex at Harwell, UKRI-STFC, DidcotOX11 0FA, United Kingdom

7. Institute of Chemistry, University of Graz, Heinrichstraße 28, 8010Graz, Austria

8. Department of Biological Sciences and Biotechnology, Universiti Kebangsaan Malaysia, 43600Bangi, SelangorMalaysia

9. Department of Chemistry, Faculty of Science, Sohag University, Sohag82524, Egypt

10. Department of Biotechnology, TU Delft, Van der Maasweg 9, 2629HZDelft, The Netherlands

11. BioHealth Field of Excellence, University of Graz, 8010Graz, Austria

Funder

?sterreichische Forschungsf?rderungsgesellschaft

Austrian Science Fund

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

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