Reduced Antinociception of Opioids in Rats and Mice by Vaccination with Immunogens Containing Oxycodone and Hydrocodone Haptens

Author:

Pravetoni Marco123,Le Naour Morgan4,Tucker Ashli M.1,Harmon Theresa M.1,Hawley Tara M.1,Portoghese Philip S.34,Pentel Paul R.123

Affiliation:

1. Minneapolis Medical Research Foundation, 701 Park Avenue, Minneapolis, Minnesota 55404, United States

2. University of Minnesota, School of Medicine, Department of Medicine, 420 Delaware Street SE, MMC 194, Suite 14-110, Phillips−Wangensteen Building, Minneapolis, Minnesota 55455, United States

3. University of Minnesota, School of Medicine, Department of Pharmacology, 6-120 Jackson Hall, 321 Church Street SE, Minneapolis Minnesota 55455, United States

4. University of Minnesota, College of Pharmacy, Department of Medicinal Chemistry, 8-101 Weaver Densford Hall, 308 Harvard Street SE, Minneapolis, Minnesota 55455, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference36 articles.

1. a2008 Department of Defense Survey of Health Related Behaviors Among Active Duty Military Personnel;U.S. Department of Defence, 2009;

2. bNational Survey on Drug Use and Health: National Findings;U.S. Department of Health and Human Services Substance Abuse and Mental Health Services Administration Office of Applied Studies, 2011;

3. Abuse of prescription drugs and the risk of addiction

4. Major increases in opioid analgesic abuse in the United States: Concerns and strategies

5. The prescription drug epidemic in the United States: A perfect storm

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