Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents-Reference-Cited by-同舟云学术

Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents

Published:2014-03-10 Issue:6 Volume:57 Page:2549-2567
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Viayna Elisabet¹²,Sola Irene¹²,Bartolini Manuela³,De Simone Angela⁴,Tapia-Rojas Cheril⁵,Serrano Felipe G.⁵,Sabaté Raimon⁶⁷,Juárez-Jiménez Jordi²⁶,Pérez Belén⁸,Luque F. Javier²⁶,Andrisano Vincenza⁴,Clos M. Victòria⁸,Inestrosa Nibaldo C.⁵,Muñoz-Torrero Diego¹²

Affiliation:

1. Laboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, E-08028 Barcelona, Spain

2. Institut de Biomedicina (IBUB), Universitat de Barcelona, E-08028 Barcelona, Spain

3. Department of Pharmacy and Biotechnology, Alma Mater Studiorum University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy

4. Department for Life Quality Studies, University of Bologna, Corso d’Augusto 237, I-47921 Rimini, Italy

5. Centro de Envejecimiento y Regeneración (CARE), Departamento de Biología Celular y Molecular, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Alameda 340, 8331150 Santiago, Chile

6. Departament de Fisicoquímica, Facultat de Farmàcia, Universitat de Barcelona, E-08028 Barcelona, Spain

7. Institut de Nanociència i Nanotecnologia (IN2UB), Universitat de Barcelona, E-08028 Barcelona, Spain

8. Departament de Farmacologia, de Terapèutica i de Toxicologia, Institut de Neurociències, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401824w

Reference105 articles.

1. Batsch, N. L.; Mittelman, M. S.World Alzheimer Report 2012. Overcoming the Stigma of Dementia;Alzheimer’s Disease International:London, 2012; http://www.alz.co.uk.

2. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

3. The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing

4. Alzheimer's disease: strategies for disease modification

5. Reassessing the amyloid cascade hypothesis of Alzheimer's disease

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