N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy
Author:
Affiliation:
1. Departments of †Chemistry, ‡Pharmacology, and §Biology, Icagen Inc., 4222 Emperor Boulevard, Durham, North Carolina 27702, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml200053x
Reference19 articles.
1. Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone
2. KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M-Channel
3. A Potassium Channel Mutation in Neonatal Human Epilepsy
4. A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family
5. A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns
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