α-Functionalized Phosphonylphosphinates: Synthesis and Evaluation as Transcarbamoylase Inhibitors-Reference-Cited by-同舟云学术

α-Functionalized Phosphonylphosphinates: Synthesis and Evaluation as Transcarbamoylase Inhibitors

Published:1999-06-18 Issue:14 Volume:42 Page:2633-2640
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Flohr Alexander¹,Aemissegger Andreas¹,Hilvert Donald¹

Affiliation:

1. Laboratorium für Organische Chemie, Swiss Federal Institute of Technology (ETH), Universitätstrasse 16, CH-8092 Zürich, Switzerland, and Departments of Chemistry and Molecular Biology, The Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991008q

Reference66 articles.

1. The first potent inhibitor of squalene synthase: a profound contribution of an ether oxygen to inhibitor-enzyme interaction

2. Novel phosphonylphosphinyl (P-C-P-C-) analogs of biochemically interesting diphosphates. Syntheses and properties of P-C-P-C-, analogs of isopentenyl diphosphate and dimethylallyl diphosphate

3. Design and synthesis of phosphonate inhibitors of glutamine synthetase

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