Toward Eradicating HIV Reservoirs in the Brain: Inhibiting P-Glycoprotein at the Blood–Brain Barrier with Prodrug Abacavir Dimers-Reference-Cited by-同舟云学术

Toward Eradicating HIV Reservoirs in the Brain: Inhibiting P-Glycoprotein at the Blood–Brain Barrier with Prodrug Abacavir Dimers

Published:2011-09-09 Issue:6 Volume:134 Page:2976-2980
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Namanja Hilda A.¹,Emmert Dana¹,Davis David A.²,Campos Christopher³,Miller David S.³,Hrycyna Christine A.¹,Chmielewski Jean¹

Affiliation:

1. Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907-2084, United States

2. HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States

3. Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja206867t

Reference44 articles.

1. Reservoirs for HIV-1: Mechanisms for Viral Persistence in the Presence of Antiviral Immune Responses and Antiretroviral Therapy

2. HIV-1 Persistence, Viral Reservoir, and the Central Nervous System in the HAART Era

3. Assessing the Efficacy of Highly Active Antiretroviral Therapy in the Brain

4. The entry of antiviral and antiretroviral drugs into the central nervous system

5. The transport of anti-HIV drugs across blood–CNS interfaces: Summary of current knowledge and recommendations for further research

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