Synthesis and Pharmacological Evaluation of 2,4-Dinitroaryldithiocarbamate Derivatives as Novel Monoacylglycerol Lipase Inhibitors-Reference-Cited by-同舟云学术

Synthesis and Pharmacological Evaluation of 2,4-Dinitroaryldithiocarbamate Derivatives as Novel Monoacylglycerol Lipase Inhibitors

Published:2012-06-14 Issue:12 Volume:55 Page:5774-5783
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kapanda Coco N.¹,Masquelier Julien²,Labar Geoffray¹,Muccioli Giulio G.²,Poupaert Jacques H.¹,Lambert Didier M.¹

Affiliation:

1. Medicinal Chemistry, Cannabinoid and Endocannabinoid Research Group, B1.73.10, Louvain Drug Research Institute (LDRI), Université Catholique de Louvain, 73 Avenue E. Mounier, B-1200 Bruxelles, Belgium

2. Bioanalysis and Pharmacology of Bioactive Lipids Research Group, B1.72.01, Louvain Drug Research Institute (LDRI), Université Catholique de Louvain, 72 Avenue E. Mounier, B-1200 Bruxelles, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3006004

Reference38 articles.

1. 2-Arachidonoylglycerol, an Endogenous Cannabinoid Receptor Ligand, Induces Accelerated Production of Chemokines in HL-60 Cells

2. Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB1 receptor-dependent G-protein activation in rat cerebellar membranes

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