Mechanistic Insights and Safety Evaluation of the Ritter Reaction Utilizing tert-Butyl Acetate as the tert-Butyl Cation Source

Author:

Roberts Scott W.1,Shaw Stephen M.1,Milne Jacqueline E.1,Cohen Dawn E.1,Tvetan Justin T.1,Tomaskevitch Joseph1,Thiel Oliver R.1

Affiliation:

1. Department of Chemical Process Research and Development, ‡Department of Analytical Research and Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

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