Application of Fragment Screening by X-ray Crystallography to β-Secretase
Author:
Affiliation:
1. Astex Therapeutics Ltd., 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0611962
Reference66 articles.
1. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2. Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
3. Purification and cloning of amyloid precursor protein β-secretase from human brain
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