Total Synthesis and Biological Evaluation of Tubulysin U, Tubulysin V, and Their Analogues-Reference-Cited by-同舟云学术

Total Synthesis and Biological Evaluation of Tubulysin U, Tubulysin V, and Their Analogues

Published:2008-12-22 Issue:2 Volume:52 Page:238-240
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Balasubramanian Ranganathan¹,Raghavan Bhooma¹,Begaye Adrian¹,Sackett Dan L.¹,Fecik Robert A.¹

Affiliation:

1. Department of Medicinal Chemistry, 308 Harvard Street SE, 8-101 Weaver-Densford Hall, University of Minnesota, Minneapolis, Minnesota 55455-0353, and Laboratory of Integrative and Medical Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, 9 Memorial Drive, Building 9, Room 1E129, Bethesda, Maryland 20892-0924

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8013579

Reference20 articles.

1. Tubulysins, New Cytostatic Peptides from Myxobacteria Acting on Microtubuli. Production, Isolation, Physico-chemical and Biological Properties.

2. Isolation, Crystal and Solution Structure Determination, and Biosynthesis of Tubulysins—Powerful Inhibitors of Tubulin Polymerization from Myxobacteria

3. Mechanism of Action of Tubulysin, an Antimitotic Peptide from Myxobacteria

4. Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product

5. Identification and Analysis of the Core Biosynthetic Machinery of Tubulysin, a Potent Cytotoxin with Potential Anticancer Activity

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