Use of a Heck Reaction for the Synthesis of a New α-Azido Phosphotyrosyl Mimetic Suitably Protected for Peptide Synthesis

Author:

Burke Terrence R.1,Liu Ding-Guo1,Gao Yang1

Affiliation:

1. Laboratory of Medicinal Chemistry, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Building 37, Rm 5C06, Bethesda, Maryland 20892-4255 tburke@helix.nih.gov

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference25 articles.

1. Synthesis of new amino acids mimicking sulfated and phosphorylated tyrosine residues

2. Protein-tyrosine phosphatases: Structure, mechanism, and inhibitor discovery

3. Burke, T. R., Jr.; Gao, Y.; Yao, Z.J. InBiomedical Chemistry:  ApplyingChemical Principles to the Understanding and Treatment of Disease; 1st ed.; Torrence, P. R., Ed.; Joh Wiley & Sons:  New York, 2000; pp 189−210.

4. Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide

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