Systematic Evaluation and Optimization of Modification Reactions of Oligonucleotides with Amines and Carboxylic Acids for the Synthesis of DNA-Encoded Chemical Libraries
Author:
Affiliation:
1. Institute of Pharmaceutical Sciences, ETH Zürich, Vladimir-Prelog Weg 1-5/10, 8093 Zürich, Switzerland
2. Philochem AG, Libernstrasse 3, 8112 Otelfingen, Switzerland
Funder
Swiss National Science Foundation
Philochem AG
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/bc500212n
Reference37 articles.
1. DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries
2. Selecting chemicals: the emerging utility of DNA-encoded libraries
3. DNA-Encoded Chemical Libraries: A Tool for Drug Discovery and for Chemical Biology
4. Small-molecule discovery from DNA-encoded chemical libraries
5. High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries
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