Serendipitous Discovery of a Zidovudine Guanidine Complex: A Superior Process for the Production of Zidovudine
Author:
Affiliation:
1. Apotex Pharmachem, Inc., 34 Spalding Drive, Brantford, Ontario, N3T 6B8, Canada
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op2000805
Reference24 articles.
1. Nucleosides. V. The Monomesylates of 1-(2'-Deoxy-β-D-lyxofuranosyl)thymine1,2
2. Interactions of azidothymidine triphosphate with the cellular DNA polymerases alpha, delta, and epsilon and with DNA primase.
3. Nucleosides. II. 5'-O-Mesylthymidine and 3'-O-Mesylthymidine1
4. Deoxyribonucleosides and related compounds. Part V. cycloThymidines and other thymidine derivatives. The configuration at the glycosidic centre in thymidine
5. Nucleosides. III. 1-(2'-Deoxy-3',5'-epoxy-β-D-threo-pentofuranosyl) thymine1,2
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1. Process parameter and kinetic study for the azidation of a zidovudine intermediate with sodium azide in microreactors;Chemical Engineering Journal;2022-02
2. General Principles and Strategies for Salting-Out Informed by the Hofmeister Series;Organic Process Research & Development;2017-08-15
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