Detecting Substrates Bound to the Secondary Multidrug Efflux Pump EmrE by DNP-Enhanced Solid-State NMR-Reference-Cited by-同舟云学术

Detecting Substrates Bound to the Secondary Multidrug Efflux Pump EmrE by DNP-Enhanced Solid-State NMR

Published:2013-10-11 Issue:42 Volume:135 Page:15754-15762
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Ong Yean Sin¹,Lakatos Andrea¹,Becker-Baldus Johanna¹,Pos Klaas M.¹,Glaubitz Clemens¹

Affiliation:

1. Institute of Biophysical Chemistry & Centre for Biomolecular Magnetic Resonance and ‡Institute of Biochemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja402605s

Reference44 articles.

1. EmrE, an Escherichia coli 12-kDa Multidrug Transporter, Exchanges Toxic Cations and H+ and Is Soluble in Organic Solvents

2. A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE

3. In Vitro Monomer Swapping in EmrE, a Multidrug Transporter from Escherichia coli, Reveals That the Oligomer Is the Functional Unit

4. Parallel topology of genetically fused EmrE homodimers

5. Conformational Changes in the Multidrug Transporter EmrE Associated with Substrate Binding

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