Elucidating a Relationship between Conformational Sampling and Drug Resistance in HIV-1 Protease-Reference-Cited by-同舟云学术

Elucidating a Relationship between Conformational Sampling and Drug Resistance in HIV-1 Protease

Published:2013-05-01 Issue:19 Volume:52 Page:3278-3288
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

de Vera Ian Mitchelle S.¹,Smith Adam N.¹,Dancel Maria Cristina A.²,Huang Xi¹,Dunn Ben M.³,Fanucci Gail E.¹

Affiliation:

1. Department of Chemistry, P.O. Box 117200, University of Florida, Gainesville, Florida 32611-7200, United States

2. Mass Spectrometry Facility, Department of Chemistry, P.O. Box 117200, University of Florida, Gainesville, Florida 32611-7200, United States

3. Department of Biochemistry and Molecular Biology, University of Florida College of Medicine Health Science Center, Gainesville, Florida 32610-0245, United States

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi400109d

Reference77 articles.

1. HIV-1 Protease: Structural Perspectives on Drug Resistance

2. Winning the Arms Race by Improving Drug Discovery against Mutating Targets

3. Evolution of Primary Protease Inhibitor Resistance Mutations during Protease Inhibitor Salvage Therapy

4. Combining mutations in HIV-1 protease to understand mechanisms of resistance

5. Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

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