Structure–Activity Relationship between the in Vivo Skin Sensitizing Potency of Analogues of Phenyl Glycidyl Ether and the Induction of Nrf2-Dependent Luciferase Activity in the KeratinoSens in Vitro Assay-Reference-Cited by-同舟云学术

Structure–Activity Relationship between the in Vivo Skin Sensitizing Potency of Analogues of Phenyl Glycidyl Ether and the Induction of Nrf2-Dependent Luciferase Activity in the KeratinoSens in Vitro Assay

Published:2011-07-22 Issue:8 Volume:24 Page:1312-1318
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Delaine Tamara¹,Niklasson Ida B.¹,Emter Roger²,Luthman Kristina³,Karlberg Ann-Therese¹,Natsch Andreas²

Affiliation:

1. Department of Chemistry, Dermatochemistry and Skin Allergy, University of Gothenburg, SE-412 96 Gothenburg, Sweden

2. Givaudan Schweiz AG, Ueberlandstrasse 138, CH-8600 Duebendorf, Switzerland

3. Department of Chemistry, Medicinal Chemistry, University of Gothenburg, SE-412 96 Gothenburg, Sweden

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx200196s

Reference27 articles.

1. Local lymph node assay — validation, conduct and use in practice

2. The local lymph node assay and the assessment of relative potency: status of validation

3. Quantification of Chemical Peptide Reactivity for Screening Contact Allergens: A Classification Tree Model Approach

4. The in vitro skin sensitization test; human cell line activation test (h-CLAT) using THP-1 cells

5. Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro

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