Influence of Phenyl Ring Disubstitution on Bisbenzimidazole and Terbenzimidazole Cytotoxicity: Synthesis and Biological Evaluation as Radioprotectors-Reference-Cited by-同舟云学术

Influence of Phenyl Ring Disubstitution on Bisbenzimidazole and Terbenzimidazole Cytotoxicity: Synthesis and Biological Evaluation as Radioprotectors

Published:2003-07-26 Issue:18 Volume:46 Page:3785-3792
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tawar Urmila¹,Jain Akash K.¹,Dwarakanath B. S.¹,Chandra Ramesh¹,Singh Yogendra¹,Chaudhury N. K.¹,Khaitan Divya¹,Tandon Vibha¹

Affiliation:

1. Dr. B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi 110007, India, Institute of Nuclear Medicine and Allied Sciences, Brig. S. K. Majumdar Road, Delhi 110054, India, and Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030114w

Reference62 articles.

1. Decondensation of constitutive heterochromatin in L cell chromosomes by a benzimidazole compound (“33258 Hoechst”)

2. Binding characteristics of Hoechst 33258 with calf thymus DNA, poly[d(A-T)] and d(CCGGAATTCCGG): multiple stoichiometries and determination of tight binding with a wide spectrum of site affinities

3. Multiple binding modes for Hoechst 33258 to DNA.

4. Binding of Hoechst 33258 to the minor groove of B-DNA

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