Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues-Reference-Cited by-同舟云学术

Characterization of Sirtuin Inhibitors in Nematodes Expressing a Muscular Dystrophy Protein Reveals Muscle Cell and Behavioral Protection by Specific Sirtinol Analogues

Published:2009-12-30 Issue:3 Volume:53 Page:1407-1411
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pasco Matthieu Y.¹²³,Rotili Dante⁴,Altucci Lucia⁵,Farina Francesca¹²,Rouleau Guy A.³,Mai Antonello⁴,Néri Christian¹²

Affiliation:

1. INSERM, Laboratory of Neuronal Cell Biology and Pathology, Center for Psychiatry and Neurosciences U894

2. Université Paris Descartes, Equipe d’accueil 4059, 75014 Paris, France

3. University of Montreal, Department of Medicine and the Center for Excellence in Neuromics, Montreal, Québec, Canada H2L 4M1

4. Pasteur Institute—Cenci-Bolognetti Foundation, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, 00185 Rome, Italy

5. Dipartimento di Patologia Generale, Facoltà di Medicina e Chirurgia, Seconda Università di Napoli, Vico L. De Crecchio 7, 80138 Napoli, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9013345

Reference23 articles.

1. Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1

2. Sirtuins — novel therapeutic targets to treat age-associated diseases

3. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

4. Therapeutic role of sirtuins in neurodegenerative disease

5. Biological and Potential Therapeutic Roles of Sirtuin Deacetylases

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