Discovery of PG545: A Highly Potent and Simultaneous Inhibitor of Angiogenesis, Tumor Growth, and Metastasis-Reference-Cited by-同舟云学术

Discovery of PG545: A Highly Potent and Simultaneous Inhibitor of Angiogenesis, Tumor Growth, and Metastasis

Published:2012-04-13 Issue:8 Volume:55 Page:3804-3813
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ferro Vito¹,Liu Ligong¹,Johnstone Ken D.¹,Wimmer Norbert¹,Karoli Tomislav¹,Handley Paul¹,Rowley Jessica¹,Dredge Keith¹,Li Cai Ping¹,Hammond Edward¹,Davis Kat¹,Sarimaa Laura¹,Harenberg Job²,Bytheway Ian¹

Affiliation:

1. Drug Design Group, Progen Pharmaceuticals Limited, Brisbane, Queensland 4076, Australia

2. Clinical Pharmacology, Faculty of Medicine Mannheim, Ruprecht-Karls University of Heidelberg, Mannheim, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201708h

Reference37 articles.

1. Angiogenesis as a therapeutic target

2. Angiogenesis: an organizing principle for drug discovery?

3. Therapeutic options to target angiogenesis in human malignancies

4. Modes of resistance to anti-angiogenic therapy

5. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

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