Mutagenesis by O6-Methyl-, O6-Ethyl-, and O6-Benzylguanine and O4-Methylthymine in Human Cells: Effects of O6-Alkylguanine-DNA Alkyltransferase and Mismatch Repair
Author:
Affiliation:
1. Chemistry of Carcinogenesis Laboratory, National Cancer Institute at Frederick, PO Box B, Frederick, Maryland 21702
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx010032f
Reference36 articles.
1. Bishop, R. E., Dunn, L. L., Pauly, G. T., Dolan, M. E., and Moschel, R. C. (1993) The role ofO6-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects ofO6-substituted guanine residues incorporated in codon 12 of the H-rasgene.Carcinogenesis14, 593−598.
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