Discovery of Potent Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 3. Amide (C-Ring) Structure−Activity Relationship and Improvement of Overall Properties of Arylthio Cinnamides-Reference-Cited by-同舟云学术

Discovery of Potent Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 3. Amide (C-Ring) Structure−Activity Relationship and Improvement of Overall Properties of Arylthio Cinnamides

Published:2001-08-01 Issue:18 Volume:44 Page:2913-2920
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pei Zhonghua¹,Xin Zhili¹,Liu Gang¹,Li Yihong¹,Reilly Edward B.¹,Lubbers Nathan L.¹,Huth Jeffery R.¹,Link James T.¹,von Geldern Thomas W.¹,Cox Bryan F.¹,Leitza Sandra¹,Gao Yi¹,Marsh Kennan C.¹,DeVries Peter¹,Okasinski Greg F.¹

Affiliation:

1. Departments of Metabolic Disease Research, Integrative Pharmacology, Advanced Technology, and Drug Analysis, Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois 60064

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010059w

Reference34 articles.

1. Leukocyte-endothelial adhesion molecules

2. The dynamic regulation of integrin adhesiveness

3. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

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