Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer-Reference-Cited by-同舟云学术

Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer

Published:2011-09-07 Issue:39 Volume:50 Page:8478-8488
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Battistutta Roberto¹²,Cozza Giorgio³,Pierre Fabrice⁴,Papinutto Elena¹,Lolli Graziano¹²,Sarno Stefania³,O’Brien Sean E.⁴,Siddiqui-Jain Adam⁴,Haddach Mustapha⁴,Anderes Kenna⁴,Ryckman David M.⁴,Meggio Flavio³,Pinna Lorenzo A.¹³

Affiliation:

1. Venetian Institute of Molecular Medicine (VIMM), Via G. Orus 2, 35129 Padova, Italy

2. Department of Chemical Sciences, University of Padova, Via Marzolo 1, 35131 Padova, Italy

3. Department of Biological Chemistry, University of Padova, Viale G. Colombo, 35131 Padova, Italy

4. Cylene Pharmaceuticals, Inc., 5820 Nancy Ridge Drive, Suite 200, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi2008382

Reference44 articles.

1. Motif Analysis of Phosphosites Discloses a Potential Prominent Role of the Golgi Casein Kinase (GCK) in the Generation of Human Plasma Phospho-Proteome

2. One‐thousand‐and‐one substrates of protein kinase CK2?

3. The Raison D'Être of Constitutively Active Protein Kinases: The Lesson of CK2

4. Protein kinase CK2: a challenge to canons

5. Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2

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