Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a New Scaffold To Develop Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies-Reference-Cited by-同舟云学术

Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a New Scaffold To Develop Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies

Published:2009-03-20 Issue:8 Volume:52 Page:2407-2419
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Colotta Vittoria¹,Lenzi Ombretta¹,Catarzi Daniela¹,Varano Flavia¹,Filacchioni Guido¹,Martini Claudia¹,Trincavelli Letizia¹,Ciampi Osele¹,Pugliese Anna Maria¹,Traini Chiara¹,Pedata Felicita¹,Morizzo Erika¹,Moro Stefano¹

Affiliation:

1. Laboratorio di Progettazione, Sintesi e Studio di Eterocicli Biologicamente Attivi, Dipartimento di Scienze Farmaceutiche, Università di Firenze, Polo Scientifico, Via Ugo Schiff, 6, 50019 Sesto Fiorentino, Italy, Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università di Pisa, Via Bonanno, 6, 56126 Pisa, Italy, Dipartimento di Farmacologia Preclinica e Clinica, Università di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy, and Molecular Modeling Section (MMS), Dipartimento...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8014876

Reference56 articles.

1. P1 and P2 Purine and Pyrimidine Receptor Ligands

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