Trapping a Labile Adduct Formed between an ortho-Quinone Methide and 2′-Deoxycytidine-Reference-Cited by-同舟云学术

Trapping a Labile Adduct Formed between an ortho-Quinone Methide and 2′-Deoxycytidine

Published:2011-02-09 Issue:5 Volume:13 Page:1186-1189
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

McCrane Michael P.¹,Weinert Emily E.¹,Lin Ying¹,Mazzola Eugene P.¹,Lam Yiu-Fai¹,Scholl Peter F.¹,Rokita Steven E.¹

Affiliation:

1. Department of Chemistry and Biochemistry and the Joint Institute for Food Safety and Applied Nutrition (JIFSAN), University of Maryland, College Park, Maryland 20742, United States, and Division of Analytical Chemistry, Spectroscopy and Mass Spectroscopy Branch in the Center for Food Safety and Nutrition of the Food and Drug Administration, College Park, Maryland 20740, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol200071p

Reference35 articles.

1. A Transient Product of DNA Alkylation Can Be Stabilized by Binding Localization

2. A general strategy for target-promoted alkylation in biological systems

3. Few constraints limit the design of quinone methide-oligonucleotide self-adducts for directing DNA alkylation

4. Immortalizing a Transient Electrophile for DNA Cross-Linking

5. Dynamic Cross-Linking Is Retained in Duplex DNA after Multiple Exchange of Strands

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