Formaldehyde-Induced DNA Cross-Link of Indolizino[1,2-b]quinolines Derived from the A−D Rings of Camptothecin-Reference-Cited by-同舟云学术

Formaldehyde-Induced DNA Cross-Link of Indolizino[1,2-b]quinolines Derived from the A−D Rings of Camptothecin

Published:2002-11-22 Issue:26 Volume:45 Page:5809-5812
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Perzyna Aurore¹,Marty Carine¹,Facompré Michael¹,Goossens Jean-François¹,Pommery Nicole¹,Colson Pierre¹,Houssier Claude¹,Houssin Raymond¹,Hénichart Jean-Pierre¹,Bailly Christian¹

Affiliation:

1. Institut de Chimie Pharmaceutique Albert Lespagnol, EA 2692, Université de Lille 2, BP 83, 59006 Lille, France, INSERM U-524 et Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, IRCL, Place de Verdun, 59045 Lille, France, and Unité de Biospectroscopie, Université de Liège au Sart-Tilman, 4000 Liège, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020235g

Reference21 articles.

1. Action of camptothecin and its derivatives on deoxyribonucleic acid

2. Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm

3. Novel Insights into Catalytic Mechanism from a Crystal Structure of Human Topoisomerase I in Complex with DNA

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