Synthesis of Ecteinascidin ET-743 and Phthalascidin Pt-650 from Cyanosafracin B

Author:

Cuevas Carmen1,Pérez Marta1,Martín María J.1,Chicharro Jose L.1,Fernández-Rivas Carolina1,Flores María1,Francesch Andrés1,Gallego Pilar1,Zarzuelo María1,de la Calle Fernando1,García Jesús1,Polanco Concepción1,Rodríguez Ignacio1,Manzanares Ignacio1

Affiliation:

1. Pharma Mar, S. A. C/ de la Calera 3, 28760-Tres Cantos, Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference25 articles.

1. (a) Rinehart, K. L.; Shield, L. S.Topics in Pharmaceutical Sciences; Breimer, D. D., Crommelin, D. J. A., Midha, K. K., Eds.; Amsterdam Medicinal Press:  Noodwijk, The Netherlands, 1989; p 613.

2. Bioactive Compounds from Aquatic and Terrestrial Sources

3. Biologically active natural products

4. Ecteinascidins 729, 743, 745, 759A, 759B, and 770: potent antitumor agents from the Caribbean tunicate Ecteinascidia turbinata

5. Antitumor tetrahydroisoquinoline alkaloids from the colonial ascidian Ecteinascidia turbinata

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