A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans-5-Oxohexahydropyrrolo[3,2-b]pyrroles (Pyrrolidine-trans-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium Methodology-Reference-Cited by-同舟云学术

A Flexible, Practical, and Stereoselective Synthesis of Enantiomerically Pure trans-5-Oxohexahydropyrrolo[3,2-b]pyrroles (Pyrrolidine-trans-lactams), a New Class of Serine Protease Inhibitors, Using Acyliminium Methodology

Published:1999-06-17 Issue:14 Volume:64 Page:5166-5175
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Macdonald Simon J. F.¹,Clarke Geoffrey D. E.¹,Dowle Michael D.¹,Harrison Lee A.¹,Hodgson Simon T.¹,Inglis Graham G. A.¹,Johnson Martin R.¹,Shah Prit¹,Upton Richard J.¹,Walls Steven B.¹

Affiliation:

1. Enzyme Chemistry 2 and Physical Sciences, GlaxoWellcome Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo990306s

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