1. Laboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Ghent University, Belgium, Laboratory of Organic and Bioorganic Chemistry, Department of Organic Chemistry, Faculty of Sciences, Ghent University, Belgium, Institut für Klinische Chemie und Pathobiochemie, Universitätsklinkum Giessen und Marburg, Germany, and Laboratory for Medicinal Chemistry, REGA Institute, Catholic University of Leuven, Belgium