Synthesis and Cytotoxic Evaluation of Cycloheximide Derivatives as Potential Inhibitors of FKBP12 with Neuroregenerative Properties-Reference-Cited by-同舟云学术

Synthesis and Cytotoxic Evaluation of Cycloheximide Derivatives as Potential Inhibitors of FKBP12 with Neuroregenerative Properties

Published:1999-08-14 Issue:18 Volume:42 Page:3615-3622
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Christner Claudia¹,Wyrwa Ralf¹,Marsch Silvia¹,Küllertz Gerhard¹,Thiericke Ralf¹,Grabley Susanne¹,Schumann Dieter¹,Fischer Gunter¹

Affiliation:

1. Max-Planck Research Unit, Enzymology of Protein Folding, Weinbergweg 22, D-06120 Halle/Saale, Germany, Hans-Knöll-Institute of Natural Products Research, Beutenbergstrasse 11, D-07745 Jena, Germany, and Department of Maxillo-Facial and Plastic Surgery, Friedrich-Schiller-University, Bachstrasse 18, D-07743 Jena, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991038t

Reference80 articles.

1. Catalysis of protein folding by prolyl isomerase

2. Protein folding: Prolyl isomerases join the fold

3. The mode of action of peptidyl prolylcis/transisomerases in vivo: binding vs. catalysis

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