Rationally Engineered Novel Glycosyltransferase UGT74DD1 from <i>Siraitia grosvenorii</i> Catalyzes the Generation of the Sweetener Mogroside III-Reference-Cited by-同舟云学术

Rationally Engineered Novel Glycosyltransferase UGT74DD1 from Siraitia grosvenorii Catalyzes the Generation of the Sweetener Mogroside III

Published:2024-08-05 Issue:32 Volume:72 Page:18214-18224
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Gong Shukun¹²,Li Congcong³⁴,Chu Qi⁵,Gao Wei⁶^ORCID,Su Ping²,Cui Guanghong²,Tang Jinfu²,Qu Ge³⁴^ORCID,Sun Zhoutong³⁴^ORCID,Guo Juan²^ORCID,Huang Luqi¹²^ORCID

Affiliation:

1. State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China

2. State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, P. R. China

3. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China

4. Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Chinese Academy of Sciences, 32 West Seventh Avenue, Tianjin Airport Economic Area, Tianjin 300308, China

5. School of Food Engineering, Yantai Key Laboratory of Nanoscience and Technology for Prepared Food, Yantai Engineering Research Center of Green Food Processing and Quality Control, Ludong University, Yantai 264025, Shandong, China

6. School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China

Funder

National Key Research and Development Program of China

China Academy of Chinese Medical Sciences

Key project at central government level: The ability to establish sustainable use of valuable Chinese medicine resources

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.4c04235

Reference43 articles.

1. Enzymatic Synthesis of Bufadienolide O -Glycosides as Potent Antitumor Agents Using a Microbial Glycosyltransferase

2. Functional Characterization and Protein Engineering of a Triterpene 3‐/6‐/2′‐ O ‐Glycosyltransferase Reveal a Conserved Residue Critical for the Regiospecificity

3. Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus

4. Discovery of plant chemical defence mediated by a two-component system involving β-glucosidase in Panax species

5. Triterpenoid-biosynthetic UDP-glycosyltransferases from plants