Inactivation of Jack Bean Urease by Nitidine Chloride from Zanthoxylum nitidum: Elucidation of Inhibitory Efficacy, Kinetics and Mechanism-Reference-Cited by-同舟云学术

Inactivation of Jack Bean Urease by Nitidine Chloride from Zanthoxylum nitidum: Elucidation of Inhibitory Efficacy, Kinetics and Mechanism

Published:2021-11-12 Issue:46 Volume:69 Page:13772-13779
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Lu Qiang¹,Tan Daopeng²,Xu Yifei³,Liu Meigui¹,He Yuqi²,Li Cailan⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Zunyi Medical University, Zhuhai Campus, Zhuhai 519041, PR China

2. College of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China

3. Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518005, PR China

4. Department of Pharmacology, Zunyi Medical University, Zhuhai Campus, Zhuhai 519041, PR China

Funder

Guizhou Science and Technology Department

National Natural Science Foundation of China

Science and Technology Foundation of Zunyi City

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.1c04801

Reference45 articles.

1. The structure-based reaction mechanism of urease, a nickel dependent enzyme: tale of a long debate

2. Ureases: Historical aspects, catalytic, and non-catalytic properties – A review

3. Synthesis of novel xanthene based analogues: Their optical properties, jack bean urease inhibition and molecular modelling studies

4. Investigation on the effect of alkyl chain linked mono-thioureas as Jack bean urease inhibitors, SAR, pharmacokinetics ADMET parameters and molecular docking studies

5. Jack Bean Urease VI. Determination of thiol and disulfide content

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