Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling

Author:

Lin Sheng-Tsai12,Tu Shih-Hsin345,Yang Po-Sheng678,Hsu Sung-Po910,Lee Wei- Hwa1112,Ho Chi-Tang13,Wu Chih-Hsiung414,Lai Yu-Hsin12,Chen Ming-Yao12,Chen Li-Ching3515

Affiliation:

1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Shuang Ho Hospital, New Taipei City, Taiwan

2. Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

3. TMU Taipei Cancer Center, Taipei Medical University, Taipei, Taiwan

4. Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

5. Breast Medical Center, Taipei Medical University Hospital, Taipei, Taiwan

6. Department of Surgery, Mackay Memorial Hospital, Taipei, Taiwan

7. Department of Medicine, Mackay Medical College, New Taipei City, Taiwan

8. Nursing and Management, Mackay Junior College of Medicine, Taipei, Taiwan

9. Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

10. Graduate Institue of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan

11. Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

12. Department of Pathology, Taipei Medical University-Shuang Ho Hospital, Jhonghe City, Taiwan

13. Department of Food Science, Rutgers University, New Brunswick, New Jersey 08901, United States

14. Department of Surgery, En Chu Kong Hospital, New Taipei City 237, Taiwan

15. Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

Funder

Ministry of Health and Welfare

Ministry of Science and Technology, Taiwan

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

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