Corynoline Suppresses Osteoclastogenesis and Attenuates ROS Activities by Regulating NF-κB/MAPKs and Nrf2 Signaling Pathways

Author:

Jin Chen12,Yu Xian-bin12,Yang Jiayi3,Lin Zhen24,Ma Run-xun12,Lin Bing-hao12,Zhang Hao-jie12,Dai Zi-han25,Xue Kaikai26,Xie Cheng-Long12,Zheng Wenhao12ORCID,Feng Yongzeng12,Xiao Jian67ORCID,Yang Lei12ORCID

Affiliation:

1. Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325000, China

2. Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou 325000, China

3. Department of Gynaecology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325000, China

4. Department of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou 510515, Guangdong, China

5. The Second School of Medicine, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China

6. Department of Burn and Wound Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China

7. Molecular Pharmacology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China

Funder

Wenzhou Medical University

Zhejiang Traditional Chinese Medicine Administration

Medical and Health Research Project of Zhejiang Province

Basic Public Welfare Research Program of Zhejiang Province

Publisher

American Chemical Society (ACS)

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