Biotransformation of Chrysin to Baicalein: Selective C6-Hydroxylation of 5,7-Dihydroxyflavone Using Whole Yeast Cells Stably Expressing Human CYP1A1 Enzyme-Reference-Cited by-同舟云学术

Biotransformation of Chrysin to Baicalein: Selective C6-Hydroxylation of 5,7-Dihydroxyflavone Using Whole Yeast Cells Stably Expressing Human CYP1A1 Enzyme

Published:2017-08-15 Issue:34 Volume:65 Page:7440-7446
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Williams Ibidapo S.¹²,Chib Shifali³,Nuthakki Vijay K.⁴,Gatchie Linda¹²,Joshi Prashant⁴,Narkhede Niteen A.⁵,Vishwakarma Ram A.⁴^ORCID,Bharate Sandip B.⁴⁶^ORCID,Saran Saurabh³,Chaudhuri Bhabatosh¹²

Affiliation:

1. Leicester School of Pharmacy, De Montfort University, Leicester, LE1 9BH, United Kingdom

2. CYP Design Limited, Innovation Centre, 49 Oxford Street, Leicester, LE1 5XY, United Kingdom

3. Fermentation Technology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

4. Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

5. Instrumentation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

6. Academy of Scientific & Innovative Research (AcSIR), CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, India

Funder

Council of Scientific and Industrial Research

Higher Education Innovation Fund

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.7b02690

Reference42 articles.

1. Acute Hepatitis after Ingestion of a Preparation of Chinese Skullcap and Black Catechu for Joint Pain

2. Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways

3. Baicalein Induces Beclin 1- and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells

4. Anticancer activity of baicalein and luteolin studied in colorectal adenocarcinoma LoVo cells and in drug-resistant LoVo/Dx cells

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