Metabolic Engineering of <i>Saccharomyces cerevisiae</i> for de Novo Dihydroniloticin Production Using Novel CYP450 from Neem (<i>Azadirachta indica</i>)-Reference-Cited by-同舟云学术

Metabolic Engineering of Saccharomyces cerevisiae for de Novo Dihydroniloticin Production Using Novel CYP450 from Neem (Azadirachta indica)

Published:2022-03-08 Issue:11 Volume:70 Page:3467-3476
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Hou Kangxin¹²^ORCID,Yu Wantong¹²,Wang Xiaojiao³,Liu Jiarou¹,Liu Yan¹,Liu Jia¹,Su Xinyao¹⁴,Zhang Xiaoli¹⁵,Xue Qiang¹,Wang Caixia¹^ORCID

Affiliation:

1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, P.R. China

2. College of Food Science and Biology, Hebei University of Science & Technology, Shijiazhuang 050000, P.R. China

3. Exchange, Development & Service Center for Science & Technology Talents, The Ministry of Science and Technology (MoST), 54 Sanlihe Road, Xicheng District, Beijing 100045, P.R.China

4. School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301607, P.R. China

5. Department of Food Science, Beijing Key Laboratory of Forestry Food Processing and Safety, College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, PR China

Funder

Ministry of Science and Technology of the People's Republic of China

China Academy of Chinese Medical Sciences

Fundamental Research Funds for the Central public welfare research institutes

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.1c07869

Reference34 articles.

1. Meliaceous Limonoids: Chemistry and Biological Activities

2. Azadirone, a Limonoid Tetranortriterpene, Induces Death Receptors and Sensitizes Human Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) through a p53 Protein-independent Mechanism

3. Cytoprotective and Anti-secretory Effects of Azadiradione Isolated from the Seeds of Azadirachta indica (neem) on Gastric Ulcers in Rat Models

4. Effects of the neem tree compounds azadirachtin, salannin, nimbin, and 6-desacetylnimbin on ecdysone 20-monooxygenase activity

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