Exposure to Succinate Leads to Steatosis in Non-Obese Non-Alcoholic Fatty Liver Disease by Inhibiting AMPK/PPARα/FGF21-Dependent Fatty Acid Oxidation

Author:

Yang Hong1,Ran Suye2,Zhou Yuxia3,Shi Qing2,Yu Jiangnan4,Wang Wenjuan5,Sun Chengqin2,Li Dengke6,Hu Yue1,Pan Chen1,Yuan Qi1,Zhen Yunhuan7,Liu Qi1,Song Lingyu1ORCID

Affiliation:

1. Department of Gastroenterology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China

2. Guizhou Medical University, Guiyang, Guizhou 550025, China

3. Department of Pathophysiology, Guizhou Medical University, Guiyang, Guizhou 550025, China

4. Department of Gastroenterology, Guizhou Hospital of the First Affiliated Hospital, Sun Yat-sen University, Guiyang, Guizhou 550000, China

5. Department of Gastroenterology, Xingyi People’s Hospital, Xingyi, Guizhou 562400, China

6. Luoyang Vocational and Technical College, Luoyang, Henan 471000, China

7. Department of Colorectal Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China

Funder

Guizhou Medical University

Department of Education of Guizhou Province

Guizhou Provincial Science and Technology Department

National Natural Science Foundation of China

Marshall Joint Laboratory Project of Affiliated Hospital of Guizhou Medical University

Affiliated Hospital of Guizhou Medical University

Publisher

American Chemical Society (ACS)

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