High-Level Production of Lacto-<i>N</i>-neotetraose in <i>Escherichia coli</i> by Stepwise Optimization of the Biosynthetic Pathway-Reference-Cited by-同舟云学术

High-Level Production of Lacto-N-neotetraose in Escherichia coli by Stepwise Optimization of the Biosynthetic Pathway

Published:2023-10-18 Issue:43 Volume:71 Page:16212-16220
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Zhang Mengwei¹²³,Zhang Kang¹²³,Liu Tongle¹²³,Wang Luyao¹²³,Wu Mengping¹²³,Gao Shengqi¹²³,Cai Bohan¹²³,Zhang Fengshan⁴,Su Lingqia¹²³,Wu Jing¹²³^ORCID

Affiliation:

1. State Key Laboratory of Food Science and Resources, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China

2. School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China

3. International Joint Laboratory on Food Safety, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China

4. Shandong Huatai Paper Co., Ltd. and Shandong Yellow Triangle Biotechnology Industry Research Institute Co. LTD, Dongying 257335, China

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Shenzhen Institute of Synthetic Biology Scientific Research Program

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.3c04856

Reference34 articles.

1. Recent understanding of human milk oligosaccharides in establishing infant gut microbiome and roles in immune system

2. Production of HMOs using microbial hosts — from cell engineering to large scale production

3. Bacteroides in the Infant Gut Consume Milk Oligosaccharides via Mucus-Utilization Pathways

4. The Schistosome Oligosaccharide Lacto-N-neotetraose Expands Gr1+Cells That Secrete Anti-inflammatory Cytokines and Inhibit Proliferation of Naive CD4+Cells: A Potential Mechanism for Immune Polarization in Helminth Infections

5. Human milk oligosaccharide effects on intestinal function and inflammation after preterm birth in pigs

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