Physiologically based Kinetic Modeling-Facilitated Quantitative In Vitro to In Vivo Extrapolation to Predict the Effects of Aloe-Emodin in Rats and Humans
Author:
Affiliation:
1. Division of Toxicology, Wageningen University and Research, Stippeneng 4, Wageningen 6708 WE, The Netherlands
Funder
Horizon 2020 Framework Programme
China Scholarship Council
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.4c00969
Reference53 articles.
1. A comprehensive overview of functional and rheological properties of aloe vera and its application in foods
2. A high-value-added application of the stems of Rheum palmatum L. as a healthy food: the nutritional value, chemical composition, and anti-inflammatory and antioxidant activities
3. Attributes of Polygonum multiflorum to transfigure red biotechnology
4. Induction of Apoptosis in HepaRG Cell Line by Aloe-Emodin through Generation of Reactive Oxygen Species and the Mitochondrial Pathway
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