Discovery Phase Agrochemical Predictive Safety Assessment Using High Content <i>In Vitro</i> Data to Estimate an <i>In Vivo</i> Toxicity Point of Departure-Reference-Cited by-同舟云学术

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Discovery Phase Agrochemical Predictive Safety Assessment Using High Content In Vitro Data to Estimate an In Vivo Toxicity Point of Departure

Published:2024-07-21 Issue:30 Volume:72 Page:17099-17120
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Bianchi Enrica¹^ORCID,Costa Eduardo²,Harrill Joshua³^ORCID,Deford Paul¹,LaRocca Jessica¹,Chen Wei¹,Sutake Zachary¹,Lehman Audrey¹,Pappas-Garton Anthony⁴,Sherer Eric¹,Moreillon Connor¹,Sriram Shreedharan¹,Dhroso Andi¹,Johnson Kamin¹^ORCID

Affiliation:

1. Corteva Agriscience, Indianapolis ,Indiana 46268, United States

2. Corteva Agriscience, Sao Paulo 05314, Brazil

3. Center for Computational Toxicology and Exposure, United States Environmental Protection Agency, Research Triangle Park ,North Carolina 27709, United States

4. Corteva Agriscience, Johnston ,Iowa 50131, United States

Funder

Corteva Agriscience

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.4c03094

Reference54 articles.

1. EPA, U. Strategic Plan to Promote the Development and Implementation of Alternative Test Methods. 2018.

2. Agency, E. C. New Approach Methodologies in Regulatory Science. 2016.

3. A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay

4. Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling

5. A phenomics approach for antiviral drug discovery

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