Octyl Ester of Ginsenoside Rh2 Induces Apoptosis and G1 Cell Cycle Arrest in Human HepG2 Cells by Activating the Extrinsic Apoptotic Pathway and Modulating the Akt/p38 MAPK Signaling Pathway-Reference-Cited by-同舟云学术

Octyl Ester of Ginsenoside Rh2 Induces Apoptosis and G1 Cell Cycle Arrest in Human HepG2 Cells by Activating the Extrinsic Apoptotic Pathway and Modulating the Akt/p38 MAPK Signaling Pathway

Published:2016-10-03 Issue:40 Volume:64 Page:7520-7529
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Chen Fang¹²,Zheng Shi-Lian¹²,Hu Jiang-Ning¹²,Sun Yong¹²,He Yue-Ming¹²,Peng Han¹²,Zhang Bing¹,McClements David Julian³,Deng Ze-Yuan¹²

Affiliation:

1. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, Jiangxi 330047, China

2. College of Food Science, Nanchang University, Nanchang, Jiangxi 330047, China

3. Department of Food Science, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

Funder

the Foundation of Jiangxi Educational Committee

the research Foundation for Young Scientists of State Key Laboratory of Food Science and Technology, Nanchang University, China

the Research Program of State Key Laboratory of Food Science and Technology, Nanchang University

the National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.6b03519

Reference41 articles.

1. Ginsenoside-Rh2 blocks the cell cycle of SK-HEP-1 cells at the G1/S boundary by selectively inducing the protein expression of p27kip1

2. Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells

3. Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells

4. Ginsenoside-Rh2-Induced Mitochondrial Depolarization and Apoptosis Are Associated with Reactive Oxygen Species- and Ca2+-Mediated c-Jun NH2-Terminal Kinase 1 Activation in HeLa Cells

5. Current Evaluation of the Millennium Phytomedicine- Ginseng (II): Collected Chemical Entities, Modern Pharmacology, and Clinical Applications Emanated from Traditional Chinese Medicine

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