Applying an Electrophilicity-Based Strategy to Develop a Novel Nrf2 Activator Inspired from Dietary [6]-Shogaol
Author:
Affiliation:
1. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, 222 Tianshui Street South, Lanzhou, Gansu 730000, China
Funder
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
General Agricultural and Biological Sciences,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.8b02442
Reference47 articles.
1. Molecular basis of the Keap1–Nrf2 system
2. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
3. Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway
4. Molecular mechanisms of Nrf2-mediated antioxidant response
5. Direct and indirect antioxidant properties of inducers of cytoprotective proteins
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