Discovery of Novel Nicotinamide Derivatives by a Two-Step Strategy of Azo-Incorporating and Bioisosteric Replacement

Author:

Ru Yifan1,Fu Wen12ORCID,Guo Sifan1,Li Xiaoyan3,Zhou Cong1ORCID,Xu Zhiping1,Cheng Jiagao1ORCID,Li Zhong14ORCID,Shao Xusheng1456ORCID

Affiliation:

1. Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

2. National Key Laboratory of Green Pesticide, Guizhou University, Guiyang 550025, Guizhou China

3. College of Humanities and Economic Management, Yantai Institute of China Agricultural University, Yantai 264670, Shandong China

4. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China

5. Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

6. Engineering Research Center of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

Funder

National Key Research and Development Program of China

Shanghai Municipal Education Commission

National Natural Science Foundation of China

Joint Institute of Tobacco and Health

National Key Laboratory of Green Pesticide / Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University

Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Municipal Education Commission

Publisher

American Chemical Society (ACS)

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