ApoE-Dependent Protective Effects of Sesamol on High-Fat Diet-Induced Behavioral Disorders: Regulation of the Microbiome-Gut

ApoE-Dependent Protective Effects of Sesamol on High-Fat Diet-Induced Behavioral Disorders: Regulation of the Microbiome-Gut–Brain Axis

Published:2019-05-22 Issue:22 Volume:67 Page:6190-6201
ISSN:0021-8561
Container-title:Journal of Agricultural and Food Chemistry
language:en
Short-container-title:J. Agric. Food Chem.

Author:

Yuan Tian¹,Chu Chuanqi²,Shi Rubing¹,Cui Tianlin¹,Zhang Xinglin¹,Zhao Yihang¹,Shi Xu¹,Hui Yan³,Pan Junru¹,Qian Rui⁴,Dai Xiaoshuang⁵,Liu Zhigang¹,Liu Xuebo¹^ORCID

Affiliation:

1. College of Food Science and Engineering, Northwest A&F University, Yangling, China

2. School of Food Science and Technology, Jiangnan University, Wuxi, China

3. Department of Food Science, University of Copenhagen, Copenhagen, Denmark

4. Food Analysis and Development Center, Beijing ZhiYunDa Technology, Co., LTD., Beijing, China

5. BGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen, China

Funder

Ministry of Science and Technology of the People's Republic of China

Ministry of Education of the People's Republic of China

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Key Research and Development Program of Shaanxi

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jafc.9b01436

Reference58 articles.

1. Overweight in midlife and risk of dementia: a 40-year follow-up study

2. High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity

3. Links Between Obesity-Induced Brain Insulin Resistance, Brain Mitochondrial Dysfunction, and Dementia

4. Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease

5. Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice

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